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Reading Post #149 / Original Topic: NovoLog not Working
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NovoLog not Working
McScrappy   United States
Posted: Jan-28-12, 01:14 PM (EST)
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Joined: Jan-28-12
Posts: 1

Wet Behind The Ears
Wet Behind The Ears


Hello I am new to the forum and look forward to learning from you guys.

My NovoLog in the past several weeks has just stopped having anywhere near the effectiveness that it had before. Either I have become severely insulin resistant or maybe I developed a tolerance to NovoLog, is that possible should I maybe switch to Humalog.

I was diagnosed with Type 1 a year ago I have been an athlete all my life weighed in at a solid 5'10 250 a year ago after many years of drug free weight training and healthy eating. Anyway in late 2009 I lose 40bs in about 5 weeks and almost die being hospitalized with a BG of 800+.
Since then I have taken my condition very seriously I have maintained a body weight of 215-220, I eat under a 75g of carbs a day and tons of veggies, I have gotten by with just 4-6 units of NovoLog before meals in the last year. Well two weeks ago even a slice of whole grain sprouted bread backed up with 8 units of NovoLog still sends me over 200 and I have to take multiple 6-8 unit shots to get my sugar down I am very frustrated and am trying to see my doc this week. Also I got another refill to rule out if the insulin was bad and my BG is still acting crazy. So i'm thinking I have developed a tolerance to NovoLog.?????

My AIC in November was 6.3




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1. RE: NovoLog not Working
mdf100   United Kingdom
Posted: Jan-29-12, 08:44 AM (EST)
In response to: message #0
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Joined: Apr-14-06
Posts: 79

Warmed Up
Warmed Up


Hi McScrappy,

Could be one of a number of things to be honest. Do you inject in the same area frequently? If so you could have developed some small patches of lipodystrophy (sp?) - these are small areas of scar tissue caused by the needles. They cause pockets where the insulin finds it difficult to get out of. If this is the case then find another place to inject for a couple of months while you heal.

Has it suddenly got a lot colder where you are? You need more insulin when its colder and less when it is hotter (can cause a swing in dosage of up to 10% believe it or not!).

Do you have an illness (cold, flu, infection, etc.). The body uses more insulin when it is fighting. You may not even feel that ill as your body is already using your immune system to fight.

It could be a bad / different batch of insulin. Try a new bottle / new batch if you are worried.

It could be stress, most (not all) diabetics need more insulin when stressed which is why some of us have different ratio's at weekend than through the working week.

Or it could just be diabetes which likes to keep us all on our toes by throwing curve balls at us just when we think we have our own condition under control.

Try the above, speak to your doctors and above all don't worry about the higher doses for now. Just keep those sugars under control and accept that every now and again this will happen.

Hope this helps and let us know how you get on.
Mark




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